beta-lactamases

[US]/[ˌbiːtə ˈlaktəmˌeɪz]/
[UK]/[ˌbiːtə ˈlaktəmˌeɪz]/
Frequency: Very High

Translation

n.Enzymes produced by bacteria that hydrolyze the beta-lactam ring of penicillin and cephalosporin antibiotics, conferring resistance to these drugs.; A family of enzymes that catalyze the hydrolysis of beta-lactam bonds.

Phrases & Collocations

beta-lactamases exist

detecting beta-lactamases

beta-lactamase production

beta-lactamases inhibit

clinical beta-lactamases

beta-lactamase genes

beta-lactamases degrade

beta-lactamase activity

beta-lactamases spread

beta-lactamase testing

Example Sentences

the study investigated the prevalence of beta-lactamases in clinical isolates.

emerging beta-lactamase variants pose a significant threat to antibiotic efficacy.

patients with infections caused by beta-lactamase-producing bacteria require alternative therapies.

rapid detection of beta-lactamases is crucial for guiding antibiotic stewardship programs.

carbapenemase beta-lactamases are particularly concerning due to their broad spectrum of activity.

researchers are developing novel inhibitors to overcome beta-lactamase resistance.

the presence of extended-spectrum beta-lactamases (esbls) is a growing public health concern.

beta-lactamase genes are often located on mobile genetic elements, facilitating their spread.

clinical laboratories routinely screen for beta-lactamases in bacterial isolates.

the increased incidence of beta-lactamase production necessitates new diagnostic approaches.

understanding beta-lactamase mechanisms is essential for developing effective antibiotics.

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