demethylases

histone demethylases regulate gene expression by removing methyl groups.

lysine demethylases are involved in epigenetic modifications.

the activity of demethylases can be inhibited by certain chemicals.

demethylases play a crucial role in development and disease.

jmjd family demethylases require iron and 2-oxoglutarate as cofactors.

researchers are studying demethylases as potential drug targets.

demethylases can both activate and repress gene transcription.

the inhibition of demethylases leads to changes in chromatin structure.

some demethylases are specific to certain histone residues.

demethylases work in concert with methyltransferases.

the expression of demethylases is often altered in cancer cells.

plant demethylases help regulate stress responses.