irreversibly

The decision to close the factory was irreversibly made.

Exposure to certain chemicals can irreversibly damage the environment.

Smoking can irreversibly harm your lungs.

The accident irreversibly changed her life.

The loss of biodiversity is an irreversibly negative consequence of deforestation.

Once the damage is done, it is irreversibly done.

The effects of climate change are irreversibly altering the planet.

The relationship between the two countries was irreversibly damaged by the conflict.

Overuse of antibiotics can irreversibly lead to antibiotic resistance.

Once you had committed murder, you are, irreversibly, a murderer.

Although chronic smokers may often have irreversibly damage to taste buds.

And once you introduce it to aspirin, the drug irreversibly binds to it.

Chris Goldscheider says his hearing was irreversibly damaged by brass instruments placed immediately behind him.

If the servers are down for even a day, our entire reputation is irreversibly destroy.

If something is irreversibly damaged, then it's permanent; the text says it is only temporary irritation.

But I also feel that something has irreversibly shifted and I feel it all the time everywhere.

Somehow the entire source of Nuronium has been irreversibly compromised.

We do not want to be irreversibly putting ourselves back into these old pathways.

Of Earth’s 37 major underground reservoirs, 21 are on track to be irreversibly emptied.