mephenytoin

mephenytoin is an anticonvulsant drug used to treat refractory epilepsy.

the metabolic pathway of mephenytoin involves specific cytochrome p450 enzymes.

researchers use mephenytoin as a probe drug to phenotype cyp2c19 activity.

dosage adjustments for mephenytoin are often necessary due to genetic polymorphisms.

adverse effects associated with mephenytoin include drowsiness and skin rash.

the clinical use of mephenytoin has declined with the introduction of safer alternatives.

hydroxylation of mephenytoin is significantly slower in poor metabolizers.

physicians monitor blood levels to prevent mephenytoin toxicity during long-term therapy.

chronic administration of mephenytoin may induce hepatic microsomal enzymes.

this study investigates the pharmacokinetics of mephenytoin in human subjects.

severe gingival hyperplasia is a potential side effect of taking mephenytoin.