Here we present the first genome-wide, single-base-resolution maps of methylated cytosines in a mammalian genome, from both human embryon...
The consequence is to inactivate the gene being methylated.
As we age, some stretches of DNA get more methylated, and others less.
Beware of methylated alcohol, which is very poisonous and should never be added to drinking water.
Newborns whose mothers suffered from depression while they were pregnant are known to have more highly methylated glucocorticoid-receptor genes than others.
I'm using methylated spirits, and it needs to be in the freezer for half an hour before you start the experiment.
They found that women abused during pregnancy were significantly more likely than others to have a child with methylated glucocorticoid-receptor genes.
What you see is the genes that got more methylated are red. The genes that got less methylated are green.
Translocations can disrupt SNRNP and move the small nucleolar RNA genes away from their imprinting center, causing them to get methylated and turned off.
If the paternal imprinting center is mutated, the region gets methylated and those genes get turned off, meaning that both the maternal and paternal genes are silenced.
In one famous experiment, when mother rats weren't attentive enough to their pups, genes in the babies that helped them manage stress were methylated and turned off.
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