polymyxins

researchers are investigating polymyxins to combat antibiotic-resistant bacteria.

polymyxins demonstrate activity against gram-negative pathogens.

the use of polymyxins is often reserved for last-resort infections.

polymyxins can cause nephrotoxicity and neurotoxicity as side effects.

clinical guidelines recommend careful monitoring when administering polymyxins.

polymyxins are a class of cyclic lipopeptide antibiotics.

the polymyxins' mechanism of action involves disrupting bacterial cell membranes.

resistance to polymyxins is emerging in some bacterial strains.

polymyxins b and e are commonly used in clinical settings.

susceptibility testing helps determine if polymyxins are effective.

the polymyxins' spectrum of activity is relatively narrow.