mephenytoin is an anticonvulsant drug used to treat refractory epilepsy.
甲苯比妥是一種用於治療難治性癲癇的抗癲癇藥。
the metabolic pathway of mephenytoin involves specific cytochrome p450 enzymes.
甲苯比妥的代謝途徑涉及特定的細胞色素P450酶。
researchers use mephenytoin as a probe drug to phenotype cyp2c19 activity.
研究人員使用甲苯比妥作為探針藥物來鑑定CYP2C19的活性。
dosage adjustments for mephenytoin are often necessary due to genetic polymorphisms.
由於遺傳多態性，甲苯比妥的劑量調整通常是必要的。
adverse effects associated with mephenytoin include drowsiness and skin rash.
與甲苯比妥相關的不良反應包括嗜睡和皮膚疹。
the clinical use of mephenytoin has declined with the introduction of safer alternatives.
隨著更安全替代藥物的出現，甲苯比妥的臨床應用已減少。
hydroxylation of mephenytoin is significantly slower in poor metabolizers.
在貧乏代謝者中，甲苯比妥的羥化作用顯著減慢。
physicians monitor blood levels to prevent mephenytoin toxicity during long-term therapy.
醫生會監測血液濃度以防止長期治療期間甲苯比妥的毒性。
chronic administration of mephenytoin may induce hepatic microsomal enzymes.
長期使用甲苯比妥可能會誘導肝臟微粒體酶。
this study investigates the pharmacokinetics of mephenytoin in human subjects.
本研究調查甲苯比妥在人體受試者中的藥代動力學。
severe gingival hyperplasia is a potential side effect of taking mephenytoin.
嚴重的牙龈增生是服用甲苯比妥的潛在副作用。
mephenytoin is an anticonvulsant drug used to treat refractory epilepsy.
甲苯比妥是一種用於治療難治性癲癇的抗癲癇藥。
the metabolic pathway of mephenytoin involves specific cytochrome p450 enzymes.
甲苯比妥的代謝途徑涉及特定的細胞色素P450酶。
researchers use mephenytoin as a probe drug to phenotype cyp2c19 activity.
研究人員使用甲苯比妥作為探針藥物來鑑定CYP2C19的活性。
dosage adjustments for mephenytoin are often necessary due to genetic polymorphisms.
由於遺傳多態性，甲苯比妥的劑量調整通常是必要的。
adverse effects associated with mephenytoin include drowsiness and skin rash.
與甲苯比妥相關的不良反應包括嗜睡和皮膚疹。
the clinical use of mephenytoin has declined with the introduction of safer alternatives.
隨著更安全替代藥物的出現，甲苯比妥的臨床應用已減少。
hydroxylation of mephenytoin is significantly slower in poor metabolizers.
在貧乏代謝者中，甲苯比妥的羥化作用顯著減慢。
physicians monitor blood levels to prevent mephenytoin toxicity during long-term therapy.
醫生會監測血液濃度以防止長期治療期間甲苯比妥的毒性。
chronic administration of mephenytoin may induce hepatic microsomal enzymes.
長期使用甲苯比妥可能會誘導肝臟微粒體酶。
this study investigates the pharmacokinetics of mephenytoin in human subjects.
本研究調查甲苯比妥在人體受試者中的藥代動力學。
severe gingival hyperplasia is a potential side effect of taking mephenytoin.
嚴重的牙龈增生是服用甲苯比妥的潛在副作用。
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