Here we present the first genome-wide, single-base-resolution maps of methylated cytosines in a mammalian genome, from both human embryon...
摘要： DNA cytosine methylation is a central epigenetic modification that has essential roles in cellular processes including genome regulation, development and disease.
The consequence is to inactivate the gene being methylated.
甲基化作用將使甲基化的基因失去活性。
來源: The Economist - TechnologyAs we age, some stretches of DNA get more methylated, and others less.
隨着年齡的增長，一些DNA片段的甲基化程度會上升，而另一些則會下降。
來源: Science 60 Seconds - Scientific American November 2020 CollectionBeware of methylated alcohol, which is very poisonous and should never be added to drinking water.
要提防甲基化酒精，那是劇毒的，永遠不能摻入飲用水。
來源: New Concept English. British Edition. Book Four (Translation)Newborns whose mothers suffered from depression while they were pregnant are known to have more highly methylated glucocorticoid-receptor genes than others.
新生兒的母親若是在懷孕期間出現抑鬱症狀，他們糖皮質激素受體基因的甲基化程度就會比其他新生兒更高。
來源: The Economist - TechnologyI'm using methylated spirits, and it needs to be in the freezer for half an hour before you start the experiment.
我打算使用甲基化酒精，它需要在冰箱裏放置半個小時才能開始實驗。
來源: Think Like a Scientist (Video Version)They found that women abused during pregnancy were significantly more likely than others to have a child with methylated glucocorticoid-receptor genes.
研究發現，孕期中遭到虐待的母親生下糖皮質激素受體基因被甲基化的幼兒的可能性要比其他母親高出得多。
來源: The Economist - TechnologyWhat you see is the genes that got more methylated are red. The genes that got less methylated are green.
你看到的是甲基化程度更高的基因是紅色的。甲基化程度較低的基因呈綠色。
來源: TED Talks (Video Edition) March 2017 CollectionTranslocations can disrupt SNRNP and move the small nucleolar RNA genes away from their imprinting center, causing them to get methylated and turned off.
SNRNP基因易位會破壞小核內核糖核蛋白（SNRPN），並將核仁小RNA基因移出印記中心，導致這些基因的甲基化沉默。
來源: Osmosis - GeneticsIf the paternal imprinting center is mutated, the region gets methylated and those genes get turned off, meaning that both the maternal and paternal genes are silenced.
如果父源印記中心突變，基因將被甲基化沉默，導致母源和父源基因都處於沉默狀態。
來源: Osmosis - GeneticsIn one famous experiment, when mother rats weren't attentive enough to their pups, genes in the babies that helped them manage stress were methylated and turned off.
在一個着名的實驗中，當母老鼠對它們的幼崽不夠關心的情況下，幼崽體內幫助它們管理壓力的基因甲基化並且隱藏了。
來源: TED-Ed (video version)Here we present the first genome-wide, single-base-resolution maps of methylated cytosines in a mammalian genome, from both human embryon...
摘要： DNA cytosine methylation is a central epigenetic modification that has essential roles in cellular processes including genome regulation, development and disease.
The consequence is to inactivate the gene being methylated.
甲基化作用將使甲基化的基因失去活性。
來源: The Economist - TechnologyAs we age, some stretches of DNA get more methylated, and others less.
隨着年齡的增長，一些DNA片段的甲基化程度會上升，而另一些則會下降。
來源: Science 60 Seconds - Scientific American November 2020 CollectionBeware of methylated alcohol, which is very poisonous and should never be added to drinking water.
要提防甲基化酒精，那是劇毒的，永遠不能摻入飲用水。
來源: New Concept English. British Edition. Book Four (Translation)Newborns whose mothers suffered from depression while they were pregnant are known to have more highly methylated glucocorticoid-receptor genes than others.
新生兒的母親若是在懷孕期間出現抑鬱症狀，他們糖皮質激素受體基因的甲基化程度就會比其他新生兒更高。
來源: The Economist - TechnologyI'm using methylated spirits, and it needs to be in the freezer for half an hour before you start the experiment.
我打算使用甲基化酒精，它需要在冰箱裏放置半個小時才能開始實驗。
來源: Think Like a Scientist (Video Version)They found that women abused during pregnancy were significantly more likely than others to have a child with methylated glucocorticoid-receptor genes.
研究發現，孕期中遭到虐待的母親生下糖皮質激素受體基因被甲基化的幼兒的可能性要比其他母親高出得多。
來源: The Economist - TechnologyWhat you see is the genes that got more methylated are red. The genes that got less methylated are green.
你看到的是甲基化程度更高的基因是紅色的。甲基化程度較低的基因呈綠色。
來源: TED Talks (Video Edition) March 2017 CollectionTranslocations can disrupt SNRNP and move the small nucleolar RNA genes away from their imprinting center, causing them to get methylated and turned off.
SNRNP基因易位會破壞小核內核糖核蛋白（SNRPN），並將核仁小RNA基因移出印記中心，導致這些基因的甲基化沉默。
來源: Osmosis - GeneticsIf the paternal imprinting center is mutated, the region gets methylated and those genes get turned off, meaning that both the maternal and paternal genes are silenced.
如果父源印記中心突變，基因將被甲基化沉默，導致母源和父源基因都處於沉默狀態。
來源: Osmosis - GeneticsIn one famous experiment, when mother rats weren't attentive enough to their pups, genes in the babies that helped them manage stress were methylated and turned off.
在一個着名的實驗中，當母老鼠對它們的幼崽不夠關心的情況下，幼崽體內幫助它們管理壓力的基因甲基化並且隱藏了。
來源: TED-Ed (video version)探索常見搜尋詞彙